The Centre for Precision Medicine (CPM) at the University Hospital Brno and the Masaryk Cancer Institute formalized their cooperation by signing a memorandum of understanding on November 4, 2025. Their shared goal is to connect cutting-edge research with clinical practice and to apply the principles of molecular genetics and personalized medicine to further enhance the quality of oncology care.
The study evaluates the experience with using a Molecular Tumor Board (MTB) in the implementation of personalized oncology treatment for patients with advanced solid tumors in whom standard therapeutic options had been exhausted. Between February 2021 and April 2025, 553 patients were enrolled in the MTB, with a median age of 61 years; women predominated (62%). The most common diagnoses included colorectal cancer, cholangiocarcinoma, and pancreatic cancer. Based on molecular profiling, targeted therapy was recommended for 59% of patients. In 17% of these cases, the therapy was actually initiated, with some patients demonstrating confirmed…
The Center for Precision Medicine at University Hospital Brno (CPM FN Brno) and the National Cancer Research Institute (NICR) have established a strategic partnership aimed at connecting top-tier research with clinical practice and jointly advancing the development of precision medicine in oncology.
On May 27, 2025, the Center for Precision Medicine at University Hospital Brno (CPM FN Brno) and the Association for Gene Therapy (Asgent) established a collaboration by signing a Memorandum of Cooperation.
On May 19, 2025, the Center for Precision Medicine at University Hospital Brno signed a Memorandum of Cooperation with the Alliance of Women with Breast Cancer. This partnership aims to strengthen education, support, and research in the diagnosis and treatment of breast cancer, with a particular focus on the application of precision medicine.
On May 2, 2025, a Memorandum of Cooperation was signed between the Center for Precision Medicine at University Hospital Brno and the patient organization VERONICA.
The aim of this agreement is to coordinate activities in the field of oncology care and precision medicine.
This retrospective study summarizes our center’s experience with the clinical management of relapsed pediatric ependymomas based on the results of comprehensive molecular profiling. The study confirmed the feasibility of this approach and its favorable safety profile. Particularly promising was the…
On April 15, 2025, the Center for Precision Medicine of the University Hospital Brno and the Czech Association for Rare Diseases (RDCR) signed a Memorandum of Cooperation.
In December 2024, the Centre for Precision Medicine at University Hospital Brno (CPM FN Brno) and Roche signed a Memorandum of Cooperation.
On November 25, 2024, the parties formalized their mutual commitment to strengthening cooperation and implementing joint activities by signing a Memorandum of Cooperation.
Diagnostic efficacy and clinical utility of whole-exome sequencing in Czech pediatric patients with rare and undiagnosed diseases